sparsentan will decrease the extent or influence of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and minimizes efficacy relevant to these substrates. Renal Impairment: Modafinil needs to be used with caution in people with critical renal impairment. Nonetheless, https://modafinil76532.win-blog.com/5722611/considerations-to-know-about-modafinil