The similar functional potencies shown by methaqualone as PAM, NAM, or agonist at the assorted GABAARs propose that the modulator targets a uniform binding web site inside the receptors, a speculation even further supported by the complete reversal of its modulatory properties on the α one mutations on allopregnanolone-mediated potentiation https://chancefqtdj.fireblogz.com/60873942/the-ultimate-guide-to-methaqualone