Rectal foam or suppositories to treat ulcerative colitis (proctitis) or for Crohn's disease affecting the rectum. An acute exacerbation is more commonly known bey a 'flare-up'. An acute exacerbation of chronic obstructive pulmonary disease (COPD) is a sudden worsening of COPD symptoms compared with the usual severity of symptoms. Spacer https://www.metooo.com/u/672d1051d5e0d01190f7f8e5