Abstract The hypoxic microenvironment is presumed to be a sanctuary for myeloid leukemia cells that causes relapse following chemotherapy. but the underlying mechanism remains elusive. Using a zebrafish xenograft model. we observed that the hypoxic hematopoietic tissue preserved most of the chemoresistant leukemic cells following the doxorubicin (Dox) treatment. https://www.ngetikin.com/bargain-MLB-Texas-Rangers-Alternate-Away-Jersey-iPhone-14-Pro-Clear-Case-p111023-save-big/